Are you thinking of getting a cosmetic procedure to smooth out wrinkles or fine lines? Chances are, you’ve come across two popular brands: Xeomin and Botox. While both are derived from botulinum toxin, they differ in several ways. In this article, we’ll explore the differences and similarities between Xeomin vs Botox, and help you determine which one may be best for you.
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What is Xeomin?
Xeomin is an FDA-approved injectable that contains botulinum toxin type A, a substance that relaxes muscles and smooths out wrinkles. It is produced by the pharmaceutical company Merz Aesthetics and was first approved in 2010. Xeomin is commonly used to treat glabellar lines (the vertical lines between the eyebrows), but it can also be used to reduce the appearance of crow’s feet and forehead lines.
Xeomin is also FDA approved to treat medical conditions such as excessive drooling blepharospasm and the treatment of cervical dystonia.
Read next – What Is Masseter Botox or Can You Get Botox Around Your Mouth
What is Botox?
Botox is a brand name for botulinum toxin type A, a neurotoxin created by a species of bacteria called Clostridium botulinum.
It has been used for cosmetic purposes since 2002 and is the most widely recognized brand name in the market. Like Xeomin, Botox is used to treat wrinkles and fine lines, particularly around the eyes, forehead, mouth or botox in your neck.
Botox treatments can also be used to treat certain conditions such as chronic migraines, excessive sweating and overactive bladder.
You can also get a botox lip flip to make your lips fuller and botox can lift your eyebrows.

How do Xeomin and Botox work?
Both Xeomin and Botox work by temporarily blocking the signals that your nerves send to your muscles. By doing so, they relax the muscles and smooth out wrinkles. The effects of both injectables are temporary and typically last for three to six months. They have both a cosmetic use and can also be used to treat certain medical conditions.
Xeomin vs Botox: Differences
Read on to hear the key differences between xeomin injections and botox.
Composition
The main difference between Xeomin and Botox is their composition. While both contain botulinum toxin type A, Xeomin also known as ‘naked botox’, meaning it does not contain any additives and accessory proteins are removed in the manufacturing process. On the other hand, Botox contains several proteins that can stimulate an immune response in some people.

Storage
Another difference between Xeomin and Botox is how they are stored. Xeomin can be stored at room temperature, while Botox needs to be refrigerated. This can make Xeomin more convenient for travel and storage purposes.
Mechanism
Botulinum toxin injections block chemical signals from nerves that cause muscles to contract. They relax the facial muscles that cause frown lines and other facial wrinkles. They both reduce facial expressions that can cause wrinkles.
Dosage
The dosing of Xeomin and Botox can also differ. Xeomin is typically administered in higher doses than Botox because it is a “naked” injectable. This means that it may take longer to see the effects of xeomin, but the effects may last longer.

Onset of Action
The onset of action of Xeomin and Botox can also differ. Xeomin typically takes longer to take effect than Botox, with results appearing within three to four days. In contrast, Botox can take effect within one to two days. The full effect of both can be seen by two weeks.
Find our more about the botox timeline.
Duration of Effect
The duration of effect of Xeomin and Botox can also vary. A xeomin treatment may last longer than Botox, with results lasting up to six months. Botox, on the other hand, typically lasts for three to four months. However, individual results may vary depending on factors such as the injection site, dosage, and the individual’s metabolism.
Allergies
Another difference between Xeomin and Botox is the risk of allergic reactions. As mentioned earlier, Botox contains several proteins that may cause an immune response in some people. This can result in an allergic reaction, which can range from mild itching and redness to more severe symptoms such as difficulty breathing and swelling of the face and throat. In contrast, Xeomin is a “naked” injectable, meaning it does not contain any additives that can trigger an allergic reaction. However, it is still important to inform your healthcare provider of any allergies you may have before getting any cosmetic injections.

Xeomin vs Botox: Similarities
Here are the similarities between xeomin and botox injectable treatments:
- Mechanism of action: Both Xeomin and Botox work by blocking the signals that cause facial muscles to contract, which can reduce the appearance of wrinkles and fine lines.
- Safety: Both Xeomin and Botox have been extensively tested and are considered safe for most people when administered by a qualified healthcare professional. They both have fda approval.
- Side effects: Both treatments can cause mild side effects such as redness, swelling, and bruising at the injection site. More serious side effects are rare but can occur. These include sagging in the face, muscle weakness, headache, and flu-like symptoms.
- No downtime: They also require no downtime or recovery time, allowing patients to return to their normal activities immediately after treatment.
Xeomin vs Botox Which one should you choose?
When it comes to choosing between Xeomin and Botox, it is important to consider your individual needs, health history and preferences, as well as the advice of your healthcare provider. Both products can be effective in reducing the appearance of wrinkles and fine lines, but they may work differently for different people. Some factors to consider include the severity of your wrinkles, the area being treated, your desired outcome, and your medical history.
Your healthcare provider can evaluate your individual needs and help you determine which product may be best for you. They may also recommend a combination of treatments, such as using Xeomin for one area and Botox for another.
Most people agree that one of the benefits of botox is that it works really well for severe forehead wrinkles.
They are both effective treatments as muscle relaxants and can help you reach your aesthetic goals.

Is Xeomin as effective as Botox?
Yes, Xeomin is considered as effective as Botox in the treatment of wrinkles and other cosmetic concerns. Both Xeomin and Botox contain the same active ingredient, which is botulinum toxin type A. This toxin works by temporarily paralyzing the muscles that cause wrinkles, thereby smoothing out the skin and reducing the appearance of lines and creases.
Which is cheaper Xeomin or Botox?
The cost of Xeomin and the cost of botox can vary depending on several factors such as the location, the provider, and the amount needed for treatment. In general, however, Xeomin tends to be slightly less expensive than Botox.
One reason for this is that Xeomin is manufactured differently than Botox, which can reduce production costs. Additionally, Xeomin is typically sold in smaller vials, which can result in a lower per-unit cost compared to Botox.
However, the cost difference between Xeomin and Botox is usually not significant, and the actual price may vary depending on the specific clinic or provider. It’s important to note that cost should not be the only factor considered when choosing between Xeomin and Botox.
Is 20 units of Xeomin the same as 20 units of Botox?
Both Xeomin and Botox injections use the same unit of measurement for dosing, which is the unit of biological activity of the botulinum toxin called “mouse units” or “U”. Therefore, 20 units of Xeomin is considered equivalent to 20 units of Botox in terms of their biological activity.
However, it’s important to note that the actual dosing and efficacy of Xeomin and Botox may vary based on several factors, including the patient’s individual anatomy, the location of injection, and the technique used by the healthcare provider. Therefore, the dosing for Xeomin and Botox may differ slightly for a given treatment area, and it’s important to follow the recommended dosing guidelines and instructions from your healthcare provider to achieve the desired results.
FAQS
- Are Xeomin and Botox the same thing? No, Xeomin and Botox are different cosmetic injectables that have different formulations and mechanisms of action.
- Which is more effective, Xeomin or Botox? The effectiveness of Xeomin and Botox may vary depending on individual factors such as the area being treated, the severity of wrinkles, and the dosage used.
- Can Xeomin and Botox be used together? Yes, Xeomin and Botox can be used together for best results. Your healthcare provider can recommend the best course of treatment based on your individual needs.
- How long does it take to see results from Xeomin and Botox? Results from Xeomin and Botox can typically be seen within a few days to a week after treatment.
- Are there any risks or side effects associated with Xeomin and Botox? While Xeomin and Botox are generally considered safe, there is a risk of side effects such as bruising, swelling, and headache. It is important to discuss any concerns or medical history with your healthcare provider before undergoing treatment
In conclusion, Xeomin and Botox are both popular cosmetic treatments that can help reduce the appearance of wrinkles and fine lines on the face. Both are botulinum toxin products. While they work in a similar way, there are differences between the two products, including their formulation, duration of effect, and risk of allergies. Ultimately, the decision of which product to use should be made in consultation with a licensed healthcare provider who can evaluate your individual needs and recommend the best course of treatment. As with any cosmetic treatment, whether you choose Xeomin or Botox, it is important to prioritize your safety and work with a qualified provider, board-certified dermatologist or plastic surgeon to achieve the best possible results.
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